Makayla Carvahlo Medeiros is the guitarist and back-up vocalist of Nuklear Intoxikation. A thrash metal band she played in with her older brother, Craig, and his friend, Kurt. The three of them also lived together as housemates. Everything went downhill when Craig's girlfriend, Veronika Wood, rammed herself into the band, driving a wedge between Makayla and Craig.

Makayla forms a bond with Ashley Sabatini over their misery from overbearing people in their lives. She is drawn to their gentle, cat-like nature. Craig disapproves of their relationship, which Veronika uses as ammo to cause a rift and drive Makayla away from the band she wants to conquer. Makayla makes a difficult, but necessary decision and the crumbling tower collapses and falls.

Makayla is cheerful, outgoing, and likes to joke around, not taking life too seriously, except for when it comes to her goals and the things she is passionate about, such as music. Like her brother, she tends to make some poor and impulsive decisions as she can let her anger and emotions get the best of her at times.